PROCAINE HYDROCHLORIDE

PRODUCT IDENTIFICATION
CAS NO. 59-46-1 (Base), 51-05-8 (HCl)

PROCAINE HYDROCHLORIDE
EINECS NO.

205-302-8
FORMULA C13H20N2O2·HCl
MOL WT. 272.77

H.S. CODE

  
SMILES

 

TOXICITY

  
SYNONYMS Novocain hydrochloride; Ethocaine; Paracain; Allocaine;
2-(Diethylamino)ethyl 4-Aminobenzoate Hydrochloride; 4-Aminobenzoic acid 2-(diethylamino)-ethyl ester hydrochloride; p-Aminobenzoyldiethylaminoethanol hydrochloride; Alocaine; Aminocaine; Anesthol; Anestil; Atoxicocaine; 4-Aminobenzoic acid, 2-(diethylamino)ethyl ester, monohydrochloride; Bernacaine; Cetain; Eugerase; Irocaine; Isocaine-Asid; Isocaine-Heisler; Jenacaine; Kerocaine; Medaject; Naucaine; Neocaine; Novocaine; Planocaine; Scurocaine; Sevicaine; Sycaine; Syncaine; Topocaine;

CLASSIFICATION

  

GENERAL DESCRIPTION OF LOCAL ANESTHETC
Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide  is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Cocaine, Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest). Tricaine is used in aquaculture, fishery and veterinary.

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE White crystalline powder
MELTING POINT 154 - 157 C
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 
AUTOIGNITION

 
NFPA RATINGS  

REFRACTIVE INDEX

  
FLASH POINT

 
STABILITY

Stable under ordinary conditions. Light Sensitive.

APPLICATIONS
Procaine, an ester anesthetic, is used as a local anesthetic agent that gives prolonged relief from pain in medicine and dentistry. It has the advantage of restricted blood vessels.
SALES SPECIFICATION
BP/USP

APPEARANCE

 White crystalline powder

ASSAY

98.5 - 101.0%
MELTING POINT

154 - 157 C

LOSS ON DRYING

0.3% max

RESIDUE ON IGNITION

0.1% max

HEAVY METALS

20ppm max
TRANSPORTATION
PACKING
25kgs in fiber drum
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: , Risk Phrases: 36/37/38, Safety Phrases: 22-26-36